|
rs1042522
|
|
Papillary thyroid carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
XRCC1 T-77C polymorphism affects the genetic susceptibility for PTC development in men, the specific combination of XRCC1 haplotypes correlates with RET/PTC incidence, CDKN1B Val109Gly significantly influences the risk of developing PTC regardless of gender and in PTC cases, selected genotypes of TP53 Arg72Pro and ATM Asp1853Asn were significantly associated with monitored tumour characteristics.
|
27314298 |
2016 |
|
rs1042522
|
|
melanoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
XPC (A2920C), XPF (T30028C), TP53 (Arg72Pro), and GSTP1 (Ile105Val) polymorphisms in prognosis of cutaneous melanoma.
|
26427666 |
2016 |
|
rs1042522
|
|
Cutaneous Melanoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
XPC (A2920C), XPF (T30028C), TP53 (Arg72Pro), and GSTP1 (Ile105Val) polymorphisms in prognosis of cutaneous melanoma.
|
26427666 |
2016 |
|
rs1042522
|
|
Xeroderma pigmentosum, group F
|
|
0.020 |
GeneticVariation
|
BEFREE |
XPC (A2920C), XPF (T30028C), TP53 (Arg72Pro), and GSTP1 (Ile105Val) polymorphisms in prognosis of cutaneous melanoma.
|
26427666 |
2016 |
|
rs1042522
|
|
XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C
|
|
0.020 |
GeneticVariation
|
BEFREE |
XPC (A2920C), XPF (T30028C), TP53 (Arg72Pro), and GSTP1 (Ile105Val) polymorphisms in prognosis of cutaneous melanoma.
|
26427666 |
2016 |
|
rs1042522
|
|
Cervix carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Women carrying the p53 Arg72Pro or p53 Pro72Pro increased the risk of cervical carcinoma (ORs and 95% CIs being 3.74 (2.65-5.30), 2.23 (1.49-3.34)).
|
19576684 |
2010 |
|
rs1042522
|
|
Adult Medulloblastoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
With regard to prognosis, disease-free survival was not significantly different among the TP53 Arg72Pro SNP</span> genotypes (P > 0.05), but the less frequent genotype (Pro/Pro) was associated with shorter overall survival of medulloblastoma patients (P = 0.021).
|
22886512 |
2012 |
|
rs1042522
|
|
Medulloblastoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
With regard to prognosis, disease-free survival was not significantly different among the TP53 Arg72Pro SNP</span> genotypes (P > 0.05), but the less frequent genotype (Pro/Pro) was associated with shorter overall survival of medulloblastoma patients (P = 0.021).
|
22886512 |
2012 |
|
rs1042522
|
|
Childhood Medulloblastoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
With regard to prognosis, disease-free survival was not significantly different among the TP53 Arg72Pro SNP</span> genotypes (P > 0.05), but the less frequent genotype (Pro/Pro) was associated with shorter overall survival of medulloblastoma patients (P = 0.021).
|
22886512 |
2012 |
|
rs1042522
|
|
Malignant neoplasm of esophagus
|
|
0.090 |
GeneticVariation
|
BEFREE |
When all 11 studies were pooled into the analysis, an increased esophageal cancer risk was significantly associated with the Pro variant of TP53 Arg72Pro in three genetic comparison models [odds ratio (OR)Pro vs. Arg=1.21, 95% confidence interval (CI): 1.05-1.39, POR=0.009; ORDominant genetic model=1.22, 95% CI: 1.09-1.37, POR=0.001; ORHomozygote model=1.40, 95% CI: 1.05-1.87, POR=0.024].
|
20389250 |
2010 |
|
rs1042522
|
|
Esophageal carcinoma
|
|
0.080 |
GeneticVariation
|
BEFREE |
When all 11 studies were pooled into the analysis, an increased esophageal cancer risk was significantly associated with the Pro variant of TP53 Arg72Pro in three genetic comparison models [odds ratio (OR)Pro vs. Arg=1.21, 95% confidence interval (CI): 1.05-1.39, POR=0.009; ORDominant genetic model=1.22, 95% CI: 1.09-1.37, POR=0.001; ORHomozygote model=1.40, 95% CI: 1.05-1.87, POR=0.024].
|
20389250 |
2010 |
|
rs1042522
|
|
Esophageal Neoplasms
|
|
0.080 |
GeneticVariation
|
BEFREE |
When all 11 studies were pooled into the analysis, an increased esophageal cancer risk was significantly associated with the Pro variant of TP53 Arg72Pro in three genetic comparison models [odds ratio (OR)Pro vs. Arg=1.21, 95% confidence interval (CI): 1.05-1.39, POR=0.009; ORDominant genetic model=1.22, 95% CI: 1.09-1.37, POR=0.001; ORHomozygote model=1.40, 95% CI: 1.05-1.87, POR=0.024].
|
20389250 |
2010 |
|
rs1042522
|
|
Malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
We used real-time PCR method to investigate the genotypic frequencies of rs2602141, rs560191 and rs689647 in 53BP1 and rs1042522 in TP53 in 640 cases of lung cancer and 685 controls.
|
24316395 |
2014 |
|
rs1042522
|
|
Carcinoma of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
We used real-time PCR method to investigate the genotypic frequencies of rs2602141, rs560191 and rs689647 in 53BP1 and rs1042522 in TP53 in 640 cases of lung cancer and 685 controls.
|
24316395 |
2014 |
|
rs1042522
|
|
Primary malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
We used real-time PCR method to investigate the genotypic frequencies of rs2602141, rs560191 and rs689647 in 53BP1 and rs1042522 in TP53 in 640 cases of lung cancer and 685 controls.
|
24316395 |
2014 |
|
rs1042522
|
|
Gallbladder Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.
|
18990008 |
2009 |
|
rs1042522
|
|
Stage IV Gallbladder Cancer AJCC v8
|
|
0.020 |
GeneticVariation
|
BEFREE |
We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.
|
18990008 |
2009 |
|
rs1042522
|
|
Stage 0 Gallbladder Cancer AJCC v8
|
|
0.020 |
GeneticVariation
|
BEFREE |
We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.
|
18990008 |
2009 |
|
rs1042522
|
|
Malignant neoplasm of gallbladder
|
|
0.020 |
GeneticVariation
|
BEFREE |
We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.
|
18990008 |
2009 |
|
rs1042522
|
|
Stage III Gallbladder Cancer AJCC v8
|
|
0.020 |
GeneticVariation
|
BEFREE |
We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.
|
18990008 |
2009 |
|
rs1042522
|
|
Stage IIB Gallbladder Cancer AJCC v8
|
|
0.020 |
GeneticVariation
|
BEFREE |
We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.
|
18990008 |
2009 |
|
rs1042522
|
|
Stage IIA Gallbladder Cancer AJCC v8
|
|
0.020 |
GeneticVariation
|
BEFREE |
We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.
|
18990008 |
2009 |
|
rs1042522
|
|
Malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
We therefore investigated the combined effects of polymorphisms in TP53 (Arg72Pro) and p21/CDKN1A (Ser31Arg) and smoking on lung cancer risk.
|
17059853 |
2007 |
|
rs1042522
|
|
Primary malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
We therefore investigated the combined effects of polymorphisms in TP53 (Arg72Pro) and p21/CDKN1A (Ser31Arg) and smoking on lung cancer risk.
|
17059853 |
2007 |
|
rs1042522
|
|
Carcinoma of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
We therefore investigated the combined effects of polymorphisms in TP53 (Arg72Pro) and p21/CDKN1A (Ser31Arg) and smoking on lung cancer risk.
|
17059853 |
2007 |